Dr Anne Bodlenner Maître de Conférences Equipe de Synthèse Organique et Molécules Bioactives Laboratoire d'Innovation Moléculaire et Applications (UMR 7042) ECPM - CNRS, Université de Strasbourg, Université de Haute Alsace 67087 Strasbourg, France E-mail : annebod@unistra.fr Complete list of publications

After graduation from ECPM in 2002, Anne Bodlenner did her PhD research on the synthesis of neamine dimers aiming at targeting HIV-1 RNA under the supervision of Pr. Patrick Pale. Then, she moved to Graz, Austria to focus on biocatalysis in the group of Pr. Kurt Faber and pursued her interest in enzymes by working on the biosynthesis of triterpene derivatives (hopanoïds) in the laboratory of Pr. Michel Rohmer. She was appointed in the Technical University Institute IUT Robert Schuman as Maître de Conférences in 2008. She continued her research in Pr. M. Rohmer's group till 2011, and then joined the team of Pr. Philippe Compain, to develop new classes of iminosugars of biological and therapeutic interest. She is now responsible of tranfering skills in running bioassays to the PhD students of the laboratory.

Patent.

Molecules which bind to the Dimerization Inititation Site (DIS) of HIV RNA, their synthesis and their applications as drugs
Pale P., Weibel J.-M., Bodlenner A., Marquet R., Paillart J.-C., Dumas P., Ennifar E., Walter P., Brevet américain WO2007125423, 78pp.

Most signifiant publications.

Tight-binding Inhibition of Jack bean α-Mannosidase by Glycoimidazole Clusters
M. M. PICHON, F. STAUFFERT, A. BODLENNER, P. COMPAIN, Org. Biomol. Chem., 2019, 17, 5801-5817.

Structural Basis of Outstanding Multivalent Effects in Jack bean α-Mannosidase Inhibition
E. HOWARD, A. COUSIDO-SIAH, M. L. LEPAGE, J. P. SCHNEIDER, A. BODLENNER, A. MITSCHLER, A. MELI, I. IZZO, A. ALVAREZ, A. PODJARNY, P. COMPAIN, Angew. Chem. Int. Ed. 2018, 57, 8002-8006.

Giant Glycosidase Inhibitors: First- and Second-Generation Fullerodendrimers with a Dense Iminosugar Shell
J.-F. NIERENGARTEN, J. P. SCHNEIDER, T. M. NGUYET TRINH, A. JOOSTEN, M. HOLLER, M. L. LEPAGE, A. BODLENNER, M. I. GARCIA-MORENO, C. ORTIZ MELLET, P. COMPAIN, Chem. Eur. J. 2018, 24, 2483-2492.

Stereodivergent Synthesis of Right- and Left-handed Iminoxylitol Heterodimers and Monomers. Study of Their Impact on β-Glucocerebrosidase Activity
F. STAUFFERT, J. SERRA VINARDELL, M. GOMEZ-GRAU, H. M.AKAKIS, I. MAVRIDOU, D. GRINBERG, L. VILAGELIU, J. CASAS, A. BODLENNER, A. DELGADO, P. COMPAIN Org. Biomol. Chem. 2017, 15, 3681-3705.

Iminosugar-Cyclopeptoid Conjugates Raise Multivalent Effect in Glycosidase Inhibition at Unprecedented High Levels
M. L. LEPAGE, J. P. SCHNEIDER, A. BODLENNER, A. MELI, F. DE RICCARDIS, M. SCHMITT, C. TARNUS, N.-T. NGUYEN-HUYNH, Y.-N. FRANCOIS, E. LEIZE-WAGNER, C. BIRCK, A. COUSIDO-SIAH, A. PODJARNY, I. IZZO, P. COMPAIN, Chem. Eur. J. 2016, 22, 5151-5155.

Towards a Molecular Lego Approach for the Diversity-oriented Synthesis of Cyclodextrin Analogues Designed as Scaffolds for Multivalent Systems
M. L. LEPAGE, J. P. SCHNEIDER, A. BODLENNER, P. COMPAIN, J. Org. Chem. 2015, 80, 10719-10733.