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Dr Damien HAZELARD Maître de Conférences Equipe de Synthèse Organique et Molécules Bioactives Laboratoire d'Innovation Moléculaire et Applications (UMR 7042) ECPM - CNRS, Université de Strasbourg, Université de Haute Alsace 67087 Strasbourg, France Tel : + 33 3 68 85 26 36 E-mail : damien.hazelard@unistra.fr    Complete list of publications |
Damien Hazelard studied chemistry at the University of Cergy-Pontoise, 30 km north of Paris.
He moved to Paris-Sud University (Orsay) where he obtained his PhD in 2005 under the direction of Dr A. Fadel on the synthesis of aminocyclobutanecarboxylic acids.
After a position as a temporary Teaching and Assistant Researcher at the University of Cergy-Pontoise, Damien joined the group of Pr Y. Hayashi at the Tokyo University of Science as a postdoctoral fellow where he worked in the field of organocatalysis.
Then he moved at the University of Strasbourg where he worked successively in the team of Pr F. Colobert and Dr. G. Hanquet then under the supervision of Pr P. Compain.
He was appointed in 2010 as Maître de Conférences at the European Engineering School of Chemistry, Polymers and Material Science (ECPM). In July 2019, he defended his HDR (Habilitation à diriger des recherches).
His main research interests are the development of new synthetic methodologies for the synthesis of nitrogen heterocycle, in particular iminosugar derivatives of therapeutic interest. From 2011 to 2014, he was extractor of Organometallic Bibliographic Notebooks. Since september 2021, Damien is the dean of the ChemBioTech studies at ECPM .
Most signifiant publications.
An Unexpected Lewis Acid-Catalyzed Cascade During the Synthesis of the DEF-Benzoxocin Ring System of Nogalamycin and Menogaril: Mechanistic Elucidation by Intermediate Trapping Experiments and Density Functional Theory Studies
H. LIU, A. G. LAPORTE, D. GÓNZALEZ PINARDO, I. FERNÁNDEZ, D. HAZELARD, P. COMPAIN, J. Org. Chem., 2024, 89, 5634-5649.
Formal Glycosylation of Quinones with exo-Glycals Enabled by Iron-mediated Oxidative Radical-polar Crossover
H. LIU, A. G. LAPORTE, D. TARDIEU, D. HAZELARD, P. COMPAIN, J. Org. Chem., 2022, 87, 13178-13194.
Stereoselective Synthesis of C,C-Glycosides from Exo-Glycals Enabled by Iron-Mediated Hydrogen Atom Transfer
Tardieu, D.; Desnoyers, M.; Laye, C.; Hazelard D.; Kern, N.; Compain, P. Org. Lett., 2019, 21, 7262-7267.
Catalytic C-H amination at its limits: challenges and solutions
Hazelard, D.; Nocquet, P.-A.; Compain, P. Org. Chem. Front. 2017, 4, 2500-2521 (Themed collection: Synthetic Approaches to Natural Products via Catalytic Processes)
Square sugars: challenges and synthetic strategies
Hazelard, D.; Compain, P. Org. Biomol. Chem. 2017, 15, 3806-3827 (2017 Hot Articles in Org. Biomol. Chem.)
Pushing the limits of catalytic C-H amination in polyoxygenated cyclobutanes
Nocquet, P.-A.; Hensienne, R.; Wencel-Delord, J.; Laigre, E.; Sidelarbi, K.; Becq, F.; Norez, C.: Hazelard, D.; Compain, P. Org. Biomol. Chem. 2016, 14, 2780-2796.
Synthesis of spirocyclopropyl γ-lactams by tandem intramolecular azetidine ring-opening/closing cascade reaction: synthetic and mechanistic aspects
Nocquet, P.-A.; Hazelard, D.; Compain, P.Tetrahedron, 2012, 22, 4117-4128.
Glycosidase Inhibition with Fullerene Iminosugar Ball: a Dramatic Multivalent Effect
Compain, P.; Decroocq, C.; Iehl, J.; Holler, M.; Hazelard, D.; Mena Barragán, T.; Ortiz Mellet, C.; Nierengarten, J.-F. Angew. Chem. Int. Ed. 2010, 49, 5753-5756.