Complete list of publications

• 2010-present

  111. Diastereoselective access to C,C-glycosyl amino acids via iron-catalyzed, auxiliary-enabled MHAT coupling
  M. LANG, D. TARDIEU, B. POUSSE, P. COMPAIN, N. KERN, Chem. Commun., 2024, 60, 3154-3157.

  

  
  

  110. Expanding the scope of the Successive Ring Expansion strategy for macrocycle and medium-sized ring synthesis: unreactive and reactive lactams
  Z. YANG, M. ARNOUX, D. HAZELARD, O. R. HUGHES, J. NABARRO, A. C. WHITWOOD, M. A. FASCIONE, C. D. SPICER, P. COMPAIN, W. P. UNSWORTH, Org. Biomol. Chem., 2024, 22, 2985-2991.

  

  
  

  109. An Unexpected Lewis Acid-Catalyzed Cascade During the Synthesis of the DEF-Benzoxocin Ring System of Nogalamycin and Menogaril: Mechanistic Elucidation by Intermediate Trapping Experiments and Density Functional Theory Studies
  H. LIU, A. G. LAPORTE, D. GÓNZALEZ PINARDO, I. FERNÁNDEZ, D. HAZELARD, P. COMPAIN, J. Org. Chem., 2024, 89, 5634-5649.

  

  
  

  108. Deconstructing Best-in-Class Neoglycoclusters as a Tool for Dissecting Key Multivalent Processes in Glycosidase Inhibition
  Y. LIANG, R. SCHETTINI, N. KERN, L. MANCIOCCHI, I. IZZO, M. SPICHTY, A. BODLENNER, P. COMPAIN, Chem. Eur. J., 2024, 30, e202304126.

  

  
  

  107. Towards a General Access to 1-Azaspirocyclic Systems via Photoinduced, Reductive Decarboxylative Radical Cyclization
  N. KIPROVA, M. DESNOYERS, R. NAROBE, A. KLUFTS-EDEL, J. CHAUD, B. KÖNIG, P. COMPAIN, N. KERN, Chem. Eur. J., 2024, e202303841 (Selected as a Hot paper by Chem. Eur. J. )

  

  
  

  106. Dissecting Key Multivalent Processes in Glycosidase Inhibition: Insights from Thermodynamic Modelling and Atomistic Simulations
  M. SPICHTY, Y. LIANG, R. SCHETTINI, I. IZZO, A. BODLENNER, P. COMPAIN, bioRxiv preprint, 2023, DOI :10.1101/2023.11.29.569169.

  

  
  

  105. A Fries-Type Rearrangement Strategy for the Construction of Stereodefined Quaternary Pseudoanomeric Centers: An Entry into C-naphthyl Ketosides
  H. LIU, M. LANG, D. HAZELARD, P. COMPAIN, J. Org. Chem, 2023, 88 , 13847-13856.

  

  
  

  104. From Sweet Molecular Giants to Square Sugars and vice versa
  P. COMPAIN, Synlett, 2023, 34 , 1866-1893.

  

  
  

  103. Recent Applications of Hexamethyldisilathiane (TMS₂S) in Organic Synthesis
  D. HAZELARD, P. COMPAIN, SynOpen, 2023, 7 , 267-271.

  

  
  

  102. Stereoselective Synthesis of Glycosyl Cyanides by TMSOTf-Mediated Ring Opening of 1,6-Anhydro Sugars
  Y. LIANG, A. G. LAPORTE, A. BODLENNER, P. COMPAIN, Eur. J. Org. Chem, 2023, 26 e202201311 (selected as Very Important Paper).

  

  
  

  101. Bambus[4,6]urils As Dual Scaffolds for Multivalent Iminosugar Presentation and Ion Transport : Access to Unprecedented Glycosidase-directed Anion Caging Agents
  M. LAFOSSE, Y. LIANG, JEREMY P. SCHNEIDER, E. CARTIER, A. BODLENNER, P. COMPAIN, M.-P. HECK, Molecules, 2022, 27, 4772 (Special issue Synthesis and Therapeutic Applications of Iminosugars)

  

  
  

  100. Formal Glycosylation of Quinones with exo-Glycals Enabled by Iron-mediated Oxidative Radical-polar Crossover
  H. LIU, A. G. LAPORTE, D. TARDIEU, D. HAZELARD, P. COMPAIN, J. Org. Chem., 2022, 87, 13178-13194

  

  
  

  99. Hybrid Multivalent Jack Bean α-Mannosidase Inhibitors: the First Example of Gold Nanoparticles Decorated with Deoxynojirimycin Inhitopes
  C. VANNI, A. BODLENNER, M. MARRADI, J. P. SCHNEIDER, M. DE LOS ANGELES RAMIREZ, S. MOYA, A. GOTI, F. CARDONA, P. COMPAIN, C. MATASSINI, Molecules, 2021, 26, 5684 (DOI :10.3390/molecules26195864) (Special issue Women in Bioorganic Chemistry).

  

  
  

  98. Nucleophilic Ring-Opening of 1,6-Anhydrosugars: Recent Advances and Applications in Organic Synthesis
  D. HAZELARD, P. COMPAIN, Eur. J. Org. Chem., 2021, 3501-3515 (Institute feature series devoted to ECPM).

  

  
  

  97. Synthesis and Glycosidase Inhibition Properties of Calix[8]arene-Based Iminosugar Click Clusters
  J. P. SCHNEIDER, S. TOMMASONE, P. DELLA SALA, C. GAETA , C. TALOTTA, C. TARNUS, P. NERI, A. BODLENNER, P. COMPAIN, Pharmaceuticals, 2020, 13, 366.

  

  
  

  96. N,O-Dialkyl deoxynojirimycin derivatives as CERT START domain ligands
  T. CASTELLAN, C. SANTOS, F. RODRIGUEZ, M. L. LEPAGE, Y. LIANG, A. BODLENNER, P. COMPAIN, Y. GENISSON, C. DEHOUX, S. BALLEREAU, Bioorg. Med. Chem. Lett., 2020, 30, 126796

  

  
  

  95. Multivalent Effect in Glycosidase Inhibition: The End of the Beginning
  P. COMPAIN, Chem. Rec., 2020, 20, 10-22.

  

  
  

  94. Metal-Free Deoxygenation of α-Hydroxy Carbonyl Compounds and Beyond
  M. M. PICHON, D. HAZELARD, P. COMPAIN, Eur. J. Org. Chem., 2019, 6320-6332.

  

  
  

  93. Stereoselective Synthesis of C,C-Glycosides from Exo-Glycals Enabled by Iron-Mediated Hydrogen Atom Transfer
  D. TARDIEU, M. DESNOYERS, C. LAYE, D. HAZELARD, N. KERN, P. COMPAIN, Org. Lett., 2019, 21, 7262-7267.

  

  
  

  92. Tight-binding Inhibition of Jack bean α-Mannosidase by Glycoimidazole Clusters
  M. M. PICHON, F. STAUFFERT, A. BODLENNER, P. COMPAIN, Org. Biomol. Chem., 2019, 17, 5801-5817.

  

  
  

  91. Selective Targeting of the Interconversion Between Glucosylceramide and Ceramide by Scaffold Tailoring of Iminosugar Inhibitors
  C. BAUDOIN-DEHOUX , T. CASTELLAN, F. RODRIGUEZ, A. RIVES, F. A. STAUFFERT, V.GARCIA, T. LEVADE, P. COMPAIN , Y. GÉNISSON, Molecules, 2019, 24 354 (DOI: 10.3390/molecules24020354).

  

  
  

  90. Conformationally Constrained Fused Bicyclic Iminosugars: Synthetic Challenges and Opportunities
  R. HENSIENNE, D. HAZELARD, P. COMPAIN, Arkivoc, 2019, part (iv), 4-43 (Special issue in honor of Stephen Hanessian).

  

  
  

  89. Book Chapter: Spiro Iminosugars: Structural Diversity and Synthetic Strategies
  D. HAZELARD, R. HENSIENNE, J.-B. BEHR, P. COMPAIN in Carbohydrate-spiro-heterocycles, Topics in Heterocyclic Chemistry, L. Somsák Ed., Springer, 2019, 57 261-290.

  

  
  

  88. Glycomimetics: Design, Synthesis and Therapeutic Applications
  P. COMPAIN, Molecules 2018, 23, 1658 (Special issue entitled: Glycomimetics: Design, Synthesis and Therapeutic Applications).

  

  
  

  87. Structural Basis of Outstanding Multivalent Effects in Jack bean α-Mannosidase Inhibition
  E. HOWARD, A. COUSIDO-SIAH, M. L. LEPAGE, J. P. SCHNEIDER, A. BODLENNER, A. MITSCHLER, A. MELI, I. IZZO, A. ALVAREZ, A. PODJARNY, P. COMPAIN, Angew. Chem. Int. Ed. 2018, 57, 8002-8006.

  

  
  

  Highlighted on the website of CNRS (click to see more details)

  
  
  

  86. An Expeditious Synthesis of 1-thiotrehalose
  D. TARDIEU, M. F. CESPEDES DAVILA, D. HAZELARD, P. COMPAIN, Synthesis 2018, 50, 3927-3930.

  

  
  

  85. One-pot, highly stereoselective synthesis of dithioacetal-α,α-diglycosides
  M. F. CÉSPEDES DÁVILA, J. P. SCHNEIDER, A. GODARD, D. HAZELARD, P. COMPAIN, Molecules 2018, 23, 914 (Special issue entitled: Glycomimetics: Design, Synthesis and Therapeutic Applications).

  

  
  

  84. Stereocontrolled synthesis of polyhydroxylated bicyclic azetidines as new class of iminosugars
  M. MALINOWSKI, R. HENSIENNE, N. KERN, D. TARDIEU, A. BODLENNER, D. HAZELARD, P. COMPAIN, Org. Biomol. Chem. 2018, 16 4688 - 4700

  

  
  

  83. Metal-Free Iodine-mediated Deoxygenation of Alcohols in α-Position to Electron-withdrawing Group
  M. M. PICHON, F. STAUFFERT, L. G. ADDANTE-MOYA, A. BODLENNER, P. COMPAIN, Eur. J. Org. Chem. 2018, 1538-1545

  

  
  

  82. Giant Glycosidase Inhibitors: First- and Second-Generation Fullerodendrimers with a Dense Iminosugar Shell
  J.-F. NIERENGARTEN, J. P. SCHNEIDER, T. M. NGUYET TRINH, A. JOOSTEN, M. HOLLER, M. L. LEPAGE, A. BODLENNER, M. I. GARCIA-MORENO, C. ORTIZ MELLET, P. COMPAIN, Chem. Eur. J. 2018, 24, 2483-2492.

  

  
  

  81. Catalytic C-H amination at its limits: challenges and solutions
  D. HAZELARD, P.-A. NOCQUET, P. COMPAIN, Org. Chem. Front. 2017, 4, 2500-2521 (Themed collection: Synthetic Approaches to Natural Products via Catalytic Processes).

  

  
  

  80. Book Chapter: Large Scale Synthesis of 2,3,4,6-Tetra-O-Benzyl-1-Deoxynojirimycin
  D. HAZELARD, M. L. LEPAGE, J. P. SCHNEIDER, M. M. PICHON, F. MASSICOT, P. COMPAIN in Carbohydrates Chemistry: Proven Synthetic Methods Vol. 4, C. Vogel & P. Murphy Eds, CRC Press, pp 303-314.

  

  
  

  79. Construction of Giant Glycosidase Inhibitors from Iminosugar-Substituted Fullerene Macromonomers
  T. M. NGUYET TRINH, M. HOLLER, J. P. SCHNEIDER, M. I. GARCÍA-MORENO, J. M. GARCÍA FERNÁNDEZ, A. BODLENNER, P. COMPAIN, C. ORTIZ MELLET, J.-F. NIERENGARTEN, J. Mat. Chem. B 2017, 5,6546-6556 (Themed issue on Carbon Nanostructures in Biology and Medicine).

  

  
  

  78. Iminosugar-Based Ceramide Mimicry for the Design of New CERT Start Domain Ligands
  C. SANTOS, F. STAUFFERT, S. BALLEREAU, C. DEHOUX, F. RODRIGUEZ, A. BODLENNER, P. COMPAIN, Y. GENISSON Bioorg. Med. Chem. 2017, 25, 1984–1989.

  

  
  

  77. Stereodivergent Synthesis of Right- and Left-handed Iminoxylitol Heterodimers and Monomers. Study of Their Impact on β-Glucocerebrosidase Activity
  F. STAUFFERT, J. SERRA VINARDELL, M. GOMEZ-GRAU, H. M.AKAKIS, I. MAVRIDOU, D. GRINBERG, L. VILAGELIU, J. CASAS, A. BODLENNER, A. DELGADO, P. COMPAIN Org. Biomol. Chem. 2017, 15, 3681-3705.

  

  
  

  76. Square sugars: challenges and synthetic strategies
  P. COMPAIN, D. HAZELARD, Org. Biomol. Chem. 2017, 15, 3806-3827 (2017 Hot Articles in Org. Biomol. Chem.).

  

  
  

  75. Book Chapter: Synthesis of Amine-Containing Heterocycles by Metathesis Reactions: Recent Advances and Opportunities
  P. COMPAIN, D. HAZELARD, in Synthesis of heterocycles by Metathesis reactions, Topics in Heterocyclic Chemistry, Prunet J. Ed., Springer, 2017, 47, 111-154.

  

  
  

  74. Understanding multivalent effects in glycosidase inhibition using C-glycoside click clusters as molecular probes
  F. STAUFFERT, A. BODLENNER, T. M. NGUYET TRINH, M. I. GARCÍA MORENO, C. ORTIZ MELLET, J.-F. NIERENGARTEN, P. COMPAIN, New. J. Chem. 2016, 40, 7421-7430.

  

  
  

  73. Investigation of original multivalent iminosugars as pharmacological chaperones for the treatment of Gaucher disease
  E. LAIGRE, D. HAZELARD, J. CASAS, J. SERRA-VINARDELL, H. MICHELAKAKIS, I. MAVRIDOU, J.M.F.G. AERTS, A. DELGADO, P. COMPAIN, Carbohydr. Res. 2016, 429, 98-104 (invited paper for a special issue devoted to glycomimetics).

  

  
  

  72. Iminosugar-Cyclopeptoid Conjugates Raise Multivalent Effect in Glycosidase Inhibition at Unprecedented High Levels
  M. L. LEPAGE, J. P. SCHNEIDER, A. BODLENNER, A. MELI, F. DE RICCARDIS, M. SCHMITT, C. TARNUS, N.-T. NGUYEN-HUYNH, Y.-N. FRANCOIS, E. LEIZE-WAGNER, C. BIRCK, A. COUSIDO-SIAH, A. PODJARNY,I.IZZO, P. COMPAIN, Chem. Eur. J. 2016, 22, 5151-5155.

  

  
  

  71. Pushing the limits of catalytic C-H amination in polyoxygenated cyclobutanes
  P.-A. NOCQUET, R. HENSIENNE, J. WENCEL-DELORD, E. LAIGRE, K. SIDELARBI, F. BECQ, C. NOREZ, D. HAZELARD, P. COMPAIN, Org. Biomol. Chem. 2016, 14, 2780-2796.

  

  
  

  70. A Convenient, Gram-scale Synthesis of 1-Deoxymannojirimycin
  F. STAUFFERT, M. L. LEPAGE, M. PICHON, D. HAZELARD, A. BODLENNER, P. COMPAIN, Synthesis 2016, 48, 1177-1180.

  

  
  

  69. Towards a Molecular Lego Approach for the Diversity-oriented Synthesis of Cyclodextrin Analogues Designed as Scaffolds for Multivalent Systems
  M. L. LEPAGE, J. P. SCHNEIDER, A. BODLENNER, P. COMPAIN, J. Org. Chem. 2015, 80, 10719-10733.

  

  
  

  68. Synthesis of a new class of iminosugars based on constrained azaspirocyclic scaffolds by way of catalytic C-H amination
  P.-A. NOCQUET, R. HENSIENNE, J. WENCEL-DELORD, E. WIMMER, D. HAZELARD, P. COMPAIN, Org. Biomol. Chem. 2015, 13, 9176-9180 (2015 Hot Articles in Org. Biomol. Chem.).

  

  
  

  67. Design, synthesis and photochemical properties of the first examples of iminosugar clusters based on fluorescent cores
  M. L. LEPAGE, A. MIRLOUP, M. RIPOLL, F. STAUFFERT, A. BODLENNER, R. ZIESSEL, P. COMPAIN, Belstein J. Org. Chem. 2015, 11, 659-667 (invited paper for a special issue entitled “Multivalency as a Chemical Organization and Action Principle”).

  

  
  

  66. Iminosugars as a new class of cholinesterase inhibitors
  C. DECROOCQ , F. STAUFFERT, O. PAMLARD , F. OULAÏDI, E. GALLIENNE, O. R. MARTIN, C. GUILLOU, P. COMPAIN, Bioorg. Med. Chem. Lett. 2015, 25, 830-833.

  

  
  

  65. The Multivalent Effect in Glycosidase Inhibition: A New, Fast-emerging Topic in Glycoscience
  P. COMPAIN, A. BODLENNER, ChemBioChem 2014, 15, 1239-1251.

  

  
  

  64. Synthesis of the First Examples of Iminosugar Clusters Based on Cyclopeptoid Cores
  M. L. LEPAGE, A. MELI, A. BODLENNER, C. TARNUS, F. DE RICARDIS, I. IZZO, P. COMPAIN, Belstein J. Org. Chem. 2014, 10, 1406-1412

  

  
  

  63. Glucocerebrosidase Enhancers for Selected Gaucher Disease Genotypes by Modification of α-1-C-Substituted Imino-D-xylitols (DIXs) by Click Chemistry
  J. SERRA-VINARDELL, L. DÍAZ, J. CASAS, D. GRINBERG, L. VILAGELIU, H. MICHELAKAKIS, I. MAVRIDOU, J.M.F.G. AERTS, C. DECROOCQ, P. COMPAIN, A. DELGADO, ChemMedChem 2014, 9, 1744-1754.

  

  
  

  62. Iminosugar-based glycopolypeptides: glycosidase inhibition with bioinspired glycoprotein analogue micellar self-assemblies
  C. BONDUELLE, J. HUANG, T. MENA-BARRAGÁN, C. ORTIZ MELLET, C. DECROOCQ, E. ETAMÉ, A. HEISE, P. COMPAIN, S. LECOMMANDOUX, Chem. Commun. 2014, 50, 3350-3352.

  

  
  

  61. Searching for Glycomimetics That Target Protein Misfolding in Rare Diseases. Successes, Failures and Unexpected Progress Made in Organic Synthesis
  P. COMPAIN, Synlett 2014, 1215-1240.

  

  
  

  60. A Convergent Strategy for the Synthesis of Second-Generation Iminosugar Clusters Using Clickable Trivalent Dendrons
  A. JOOSTEN, J. P. SCHNEIDER, M. L. LEPAGE, C. TARNUS, A. BODLENNER, P. COMPAIN, Eur. J. Org. Chem. 2014, 1866-1872.

  

  
  

  59. A Systematic Investigation of Iminosugar Click Clusters as Pharmacological Chaperones for the Treatment of Gaucher Disease
  A. JOOSTEN, C. DECROOCQ, J. DE SOUSA, J. SCHNEIDER, E. ETAME, A. BODLENNER, T. D. BUTTERS, P. COMPAIN, ChemBioChem 2014, 15, 309-319.

  

  
  

  58. Rescue of Functional CFTR Channels in Cystic Fibrosis: A Dramatic Multivalent Effect Using Iminosugar Clusters-based Correctors
  P. COMPAIN, C. DECROOCQ, A. JOOSTEN, J. DE SOUSA, D. RODRÍGUEZ-LUCENA, T. D. BUTTERS, J. BERTRAND, R. CLÉMENT, C. BOINOT, F. BECQ, C. NOREZ, ChemBioChem 2013, 15, 2050-2058.

  

  
  

  57. The Multivalent Effect in Glycosidase Inhibition: Probing the Influence of Valency, Peripheral Ligand Structure and Topology with Cyclodextrin-based Iminosugar Click Clusters
  C. DECROOCQ, A. JOOSTEN, R. SERGENT, T. MENA BARRAGAN, C. ORTIZ MELLET, P. COMPAIN, ChemBioChem 2013, 15, 2038-2049.

  

  
  

  56. Synthesis of 4-Membered Carbasugars by way of Stereoselective SmI₂-Mediated Aldehyde-alkene Cyclization
  P.-A. NOCQUET, D. HAZELARD, G. GRUNTZ, P. COMPAIN, J. Org. Chem. 2013, 78, 6751–6757.

  

  
  
  

  55. Stereoselective Synthesis of α-Glycosyl Azides by TMSOTf-mediated Ring Opening of 1,6-Anhydrosugars
  M. LEPAGE, A. BODLENNER, P. COMPAIN, Eur. J. Org. Chem. 2013, 1963-1972.

  

  
  
  

  54. Synthesis of spirocyclopropyl γ-lactams by tandem intramolecular azetidine ring-opening/closing cascade reaction: synthetic and mechanistic aspects
  P.-A. NOCQUET, D. HAZELARD, P. COMPAIN, Tetrahedron 2012, 68, 4117-4128.

  

  
  
  

  53. Cyclodextrin-Based Iminosugar Click Clusters: The First Examples of Multivalent Pharmacological Chaperones for the Treatment of Lysosomal Storage Disorder
  C. DECROOCQ, D. RODRIGUEZ-LUCENA, K. IKEDA, N. ASANO, P. COMPAIN, ChemBioChem 2012, 13, 661-664.

  

  
  
  

  52. Synthesis of Spirocyclopropyl γ-Lactams by Way of a New, Highly Stereoselective Tandem Intramolecular Azetidine Ring-Opening/Closing Cascade Reaction
  P.-A. NOCQUET, D. HAZELARD, P. COMPAIN, Eur. J. Org. Chem., 2011, 6619-6623.

  

  
  
  

  51. The Multivalent Effect in Glycosidase Inhibition: Probing the Influence of Architectural Parameters with Cyclodextrin-based Iminosugar Click Clusters
  C. DECROOCQ, D. RODRIGUEZ-LUCENA, V. RUSSO, T. MENA BARRAGÁN, C. ORTIZ MELLET, P. COMPAIN, Chem. Eur. J., 2011, 17, 13825-13831.

  

  
  
  

  50. Synthesis of Azide-armed α-1-C-Alkyl-imino-D-xylitol Derivatives as Key Building Blocks for the Preparation of Iminosugar Click Conjugates
  C. DECROOCQ, L. MAMANI LAPARRA, D. RODRIGUEZ-LUCENA, P. COMPAIN, J. Carbohydr. Chem. 2011, 30, 559-574. (European Young Investigator Workshop Special issue)

  

  
  
  

  49. 1-C-Alkyl imino-D-xylitol and -L-arabinitol derivatives obtained via nucleophilic addition to pentose-derived N-tert-butanesulfinyl imines: sugar- versus chiral auxiliary-induced stereoselectivity
  F. OULAÏDI, E. GALLIENNE, P. COMPAIN, O. R. MARTIN, Tetrahedron: Asymmetry 2011, 22, 609-612.

  

  
  
  

  48. Concise Synthesis of Bicyclic Aminals by Way of Catalytic Intramolecular C-H Amination and Evaluation of their Reactivity as Iminium Precursors
  D. RODRíGUEZ-LUCENA, M. S. T. MORIN, P. COMPAIN, Lett. Org. Chem. 2011, 8, 155-162.

  

  
  
  

  47. Second Generation Iminoxylitol-based Pharmacological Chaperones for the Treatment of Gaucher Disease
  F. OULAÏDI, S. FRONT-DESCHAMPS, E. GALLIENNE, E. LESELLIER, K. IKEDA, N. ASANO, P. COMPAIN, O. R. MARTIN, ChemMedChem 2011, 6, 353-361.

  

  
  
  

  46. Glycosidase Inhibition with Fullerene Iminosugar Ball: a Dramatic Multivalent Effect
  P. COMPAIN, C. DECROOCQ, J. IEHL, M. HOLLER, D. HAZELARD, T. MENA BARRAGÁN, C. ORTIZ MELLET, J.-F. NIERENGARTEN, Angew. Chem. Int. Ed. 2010, 49, 5753-5756.

  

  
  
  

  45. Synthesis of new β-1-C-alkylated imino-L-iditols. A comparative study of their activity as β-glucocerebrosidase inhibitors
  W. SCHÖNEMANN, E. GALLIENNE, P. COMPAIN, K. IKEDA, N. ASANO, O. R. MARTIN, Bioorg. Med. Chem. 2010, 18, 2645-2650.

  

  
  
  

• 2005-2009

  44. Tactics and Strategies for the Synthesis of Iminosugar C-glycosides: a Review
  P. COMPAIN, V. CHAGNAULT, O. R. MARTIN, Tetrahedron: Asymmetry 2009, 20, 672-711. (Invited review for a special issue dedicated to G. W. J. Fleet - Oxford University)

  

  
  

  

  
  
  

  43. Stereodivergent Access to Polyhydroxylated 10-Azabicyclo[4.3.1]decanes as New Calystegine Analogs
  V. CHAGNAULT, P. COMPAIN, K. LEWINSKI, K. IKEDA, N. ASANO, O. R. MARTIN, J. Org. Chem. 2009, 74, 3179-3182.

  

  
  
  

  42. Metal-Free One-Pot Oxidative Amidation of Aldoses with Functionalized Amines
  L. COLOMBEAU, T. TENIN, P. COMPAIN, O. R. MARTIN, J. Org. Chem. 2008, 73, 8647-8650.

  

  
  
  

  41. Iterative Multifunctionalization of Unactivated C-H Bonds in Piperidines by way of Intramolecular Rh(II)-catalyzed Aminations
  S. TOUMIEUX, P. COMPAIN, and O. R. MARTIN, J. Org. Chem. 2008, 73, 2155-2162.

  

  
  
  

  40. Synthesis of 4-O-glycosylated 1-deoxynojirimycin derivatives as disaccharide mimics-based inhibitors of human β-glucocerebrosidase
  C. BOUCHERON, S. TOUMIEUX, P. COMPAIN, O. R. MARTIN, K. IKEDA and N. ASANO, Carbohydr. Res. 2007, 342, 1960-1965.

  

  
  
  

  39. Intramolecular Rhodium-catalyzed Activation of α-Amino C-H Bonds: Decisive Influence of Conformational Factors in the Synthesis of Bicyclic Aminals from N-Sulfamoyloxyacetyl Azacycloalkanes
  M. S. T. MORIN, S. TOUMIEUX, P. COMPAIN, S. PEYRAT and J. KALINOWSKA-TLUSCIK, Tetrahedron Lett. 2007, 48, 8531-8535.

  

  
  
  

  38. Review article: Olefin-Metathesis of Amine-containing Systems: Beyond the Current Consensus
  P. COMPAIN, Adv. Synth. Catal. 2007, 349, 1829-1846.

  

  
  
  

  37. Design and Synthesis of Highly Potent and Selective Pharmacological Chaperones for the Treatment of Gaucher Disease
  P. COMPAIN, O. R. MARTIN, C. BOUCHERON, G. GODIN, L. YU, K. IKEDA and N. ASANO, ChemBioChem 2006, 7, 1356-1359.

  

  
  
  

  36. New Aspects of Catalytic Intramolecular C-H Amination: Unexpected Formation of a Seven-Membered Ring in Nitrogen-Containing Systems
  S. TOUMIEUX, P. COMPAIN, O. R. MARTIN and M. SELKTI, Org. Lett. 2006, 8, 4493-4496.
  
  35. α-1-C-Octyl-1-deoxynojirimycin as a Pharmacological Chaperone for Gaucher Disease
  L. YU, K. IKEDA, A. KATO, I. ADACHI, G. GODIN, P. COMPAIN, O. R. MARTIN and N. ASANO, Bioorg. Med. Chem. 2006, 14, 7736-7744.
  
  34. A Stereodivergent Approach to 1-Deoxynojirimycin, 1-Deoxygalactonojirimycin and 1-Deoxymannojirimycin Derivatives
  C. BOUCHERON, P. COMPAIN and O. R. MARTIN Tetrahedron Lett. 2006, 47, 3081-3084.
  
  33. Looking Forward : A Glance Into the Future of Organic Chemistry
  P. COMPAIN, V. DESVERGNES, C. OLLIVIER, F. ROBERT, F. SUZENET, M. BARBOIU, P. BELMONT, Y. BLÉRIOT, F. BOLZE, S. BOUQUILLON, E. BOURGUET, B. BRAIDA, T. CONSTANTIEUX, L. DÉSAUBRY, D. DUPONT, S. GASTALDI, F. JÉROME, S. LEGOUPY, X. MARAT, M. MIGAUD, N. MOITESSIER, S. PAPOT, F. PÉRI, M. PETIT, S. PY, E. SCHULZ, I. TRANOY-OPALINSKI, B. VAUZEILLES, P. VAYRON, L. VERGNES, S. VIDAL and S. WILMOUTH New J. Chem. 2006, 30, 823-831.
  
  32. Alchimies Futures : Compte Rendu de l'Expérience ESYOP
  P. COMPAIN, V. DESVERGNES, C. OLLIVIER, F. ROBERT, F. SUZENET, M. BARBOIU, P. BELMONT, Y. BLÉRIOT, F. BOLZE, S. BOUQUILLON, E. BOURGUET, B. BRAIDA, T. CONSTANTIEUX, L. DÉSAUBRY, D. DUPONT, S. GASTALDI, F. JÉROME, S. LEGOUPY, X. MARAT, M. MIGAUD, N. MOITESSIER, S. PAPOT, F. PÉRI, M. PETIT, S. PY, E. SCHULZ, I. TRANOY-OPALINSKI, B. VAUZEILLES, P. VAYRON, L. VERGNES, S. VIDAL and S. WILMOUTH C. R. Chimie 2006, 9, 127-140.
  
  31. Intramolecular Metal-catalyzed Amination of Pseudo Anomeric C-H Bonds
  S. TOUMIEUX, P. COMPAIN and O. R. MARTIN Tetrahedron Lett. 2005, 46, 4731-4735.
  
  30. General Synthesis and Biological Evaluation of α-1-C-Substituted Derivatives of Fagomine (2-Deoxynojirimycin-α-C-Glycosides)
  J.-Y. GOUJON, D. GUEYRARD, P. COMPAIN, O. R. MARTIN, K. IKEDA, A. KATO and N. ASANO Bioorg. Med. Chem. 2005, 13, 2313-2324.
  
  29. Design and Synthesis of Iminosugar-based Inhibitors of Glucosylceramide Synthase: a Search for New Therapeutic Agents Against Gaucher Disease
  C. BOUCHERON, V. DESVERGNES, P. COMPAIN, O. R. MARTIN, A. LAVI, M. MACKEEN, M. WORMALD, R. A. DWEK, and T. D. BUTTERS Tetrahedron: Asymmetry 2005, 16, 1747-1756.
  
  

• 2004 and before

  28. Synthesis and Biological Evaluation of the First Example of an Eight-membered Iminoalditol
  G. GODIN, E. GARNIER, P. COMPAIN, O. R. MARTIN, K. IKEDA and N. ASANO Tetrahedron Lett. 2004, 45, 579-582.
  
  27. α-1-C-Alkyl-1-deoxynojirimycin Derivatives as Potent and Selective Inhibitors of Intestinal Isomaltase: Remarkable Effect of the Alkyl Chain Length on Glycosidase Inhibitory Profile
  G. GODIN, P. COMPAIN, O. R. MARTIN, K. IKEDA, L. YU and N. ASANO Bioorg. Med. Chem. Lett. 2004, 14, 5991-5995.
  
  26. 1,3-Dipolar Cycloaddition of Nitrilimines to 2,4-Disubstituted-3H-1,5-Benzodiazepines: Remarkable Effect of C4-Substituent on Diastereoselectivity
  N. KHADIJA, A. BAOUID, A. HASNAOUI, M. SELKTI and P. COMPAIN New J. Chem. 2003, 27, 1644-1648.
  
  25. General Access to Iminosugar C-Glycoside Building Blocks by Means of Cross-Metathesis: A Gateway to Glycoconjugate Mimetics
  G. GODIN, P. COMPAIN and O. R. MARTIN Org. Lett. 2003, 5, 3269-3272.
  
  24. 2-Naphtylmethyl (NAP) as a Versatile Amino Protecting Group Removable Chemoselectively Under Mild Conditions
  G. GODIN, P. COMPAIN and O. R. MARTIN Synlett. 2003, 2065-2067.
  
  23. Review article: Design, Synthesis and Biological Evaluation of Iminosugar-based Glycosyltransferase Inhibitors
  P. COMPAIN and O. R. MARTIN Curr. Top. Med. Chem. 2003, 3, 541-560.
  
  22. Ring-opening Reactions of Iminosugars-based Aziridines: Application to the General Synthesis of α-1-C-substituted Derivatives of Fagomine
  J.-Y. GOUJON, D. GUEYRARD, P. COMPAIN, O. R. MARTIN and N. ASANO Tetrahedron: Asymmetry 2003, 14, 1969-1972.
  
  21. First Stereocontrolled Synthesis and Biological Evaluation of 1,6-Dideoxy-L-nojirimycin
  A. BORDIER, P. COMPAIN, O. R. MARTIN, K. IKEDA and N. ASANO, Tetrahedron: Asymmetry 2003, 14, 47-51.
  
  20. Iminosugars: Recent Insights Into Their Bioactivity and Potential As Therapeuthic Agents - Preface
  O. R. MARTIN and P. COMPAIN Curr. Top. Med. Chem. 2003, 3(5), i-iv.
  
  19. Peri- and Regioselective Synthesis of New Heterocyclic Compounds From 1,5-Benzodiazepines
  S. ELHAZAZI, A. BAOUID, A. HASNAOUI and P. COMPAIN, Synth. Commun. 2003, 33, 19-27.
  
  18. Synthesis of a Novel Heterocyclic Ring System By Way of Highly Regio- and Chemoselective 1,3-dipolar Cycloaddition of Nitrilimines to 1,3,4-Benzotriazepin-5-one Derivatives
  R. JALAL, M. EL MESSAOUDI, A. HASNAOUI, M.-H. ESSEFAR, M. SELKTI, J. P. LAVERGNE and P. COMPAIN, New J. Chem. 2002, 26, 1545-1548.
  
  17. A General Strategy for the Practical Synthesis of Nojirimycin C-Glycosides. Extension to the First Reported Example of an Iminosugar 1-Phosphonate
  G. GODIN, P. COMPAIN, G. MASSON and O. R. MARTIN, J. Org. Chem. 2002, 67, 6960-6970.
  
  16. Lewis Acid Promoted Cyclocondensations of α-Ketophosphonoenoates with Dienes. From Diels-Alder to Hetero Diels-Alder
  S. HANESSIAN and P. COMPAIN, Tetrahedron 2002, 58, 6521-6529.
  
  15. Review article: Carbohydrate Mimetics-Based Glycosyltransferase Inhibitors
  P. COMPAIN and O. R. MARTIN Bioorg. Med. Chem. 2001, 9, 3077-3092.
  
  14. Highly Peri-, Regio- and Diastereoselective 1,3-dipolar Cycloaddition of Mesitonitrile Oxide to 1,7-Dimethyl-2,3-dihydro-1H-1,4-diazepines: Unexpected One-step Formation of a New Triheterocyclic framework
  A. BAOUID, S. ELHAZAZI, A. HASNAOUI, P. COMPAIN, J.-P. LAVERGNE and F. HUET, New J. Chem. 2001, 25, 1479-1481.
  
  13. Enzymatic Glycosylation of Contulakin-G, a Glycopeptide Isolated from Conus Venom, with a Mammalian ppGalNAc-transferase
  A. G. CRAIG, M. PARK, W. H. FISCHER, J. KANG, P. COMPAIN and F. PILLER Toxicon 2001, 39, 809-815.
  
  12. First Total Synthesis of (+)-Hyacinthacine A2
  L. RAMBAUD, P. COMPAIN and O. R. MARTIN Tetrahedron: Asymmetry 2001, 12, 1807-1809.
  11. Synthesis of a Polyhydroxylated Tetrahydro-4H-1,2,3-triazolo[1,5-a]azepin, a Higher Homolog of "Nojiritriazole", and of a Related C-Disaccharide
  K. TEZUKA, P. COMPAIN and O. R. MARTIN Synlett 2000, 1837-1839.
  
  10. A New, Stereocontrolled Approach to Iminosugar C-Glycosides from L-Sorbose
  G. MASSON, P. COMPAIN and O. R. MARTIN Org. Lett. 2000, 2, 2971-2974.
  
  

  9. Revised Structure of a Homonojirimycin Isomer from Aglaonema Treubii: First Example of a Naturally Occurring α-Homoallonojirimycin
  O. R. MARTIN, P. COMPAIN, H. KIZU and N. ASANO, Bioorg. Med. Chem. Lett. 1999, 9, 3171-3174.
  
  8. A Facile Synthesis of 3-alcoxy and 3-amino pyrroles
  V. DESVERGNES-BREUIL, P. COMPAIN, J. M. VATELE and J. GORE, Tetrahedron Lett. 1999, 40, 8789-8792.
  
  7. Reaction of the Lithio-derivative of Methoxy allene with SAMP-Hydrazones: An Access to Enantiopure 3-pyrrolines
  V. DESVERGNES-BREUIL, P. COMPAIN, J. M. VATELE and J. GORE, Tetrahedron Lett. 1999, 40, 5009-5012.
  
  6. Catalyzed Formation of g-Butyrolactones From 4-Trimethylsilyl-3-Alkyn-1-Ols : Synthetic Applications and Mechanistic Aspects
  P. COMPAIN, J. GORE and J. M. VATELE, Tetrahedron 1996, 52, 10405-10416.
  
  5. Rearrangement of α-Hydroxyimines to α-Amino Ketones : Mechanistic Aspects and Synthetic Applications
  P. COMPAIN, J. GORE and J. M. VATELE, Tetrahedron 1996, 52, 6647-6664.
  
  4. A New and Convenient Synthesis of 1-Benzyl-1-Azaspiro[5.5]Undecan-8-One: A Formal Synthesis of (+/-)-Perhydrohistrionicotoxine.
  P. COMPAIN, J. GORE and J. M. VATELE, Synth. Commun. 1995, 25, 3075-3080.
  
  3. Thermal Rearrangement of Enantioenriched α-Hydroxyimines -II : Formal Synthesis of (-)-Perhydrohistrionicotoxine
  P. COMPAIN, J. GORE and J. M. VATELE, Tetrahedron Lett. 1995, 36, 4063-4064.
  
  2. Thermal Rearrangement of Enantioenriched α-Hydroxyimines -I : Enantiocontrolled Synthesis of α-Substitued α-Amino Ketones
  P. COMPAIN, J. GORE and J. M. VATELE, Tetrahedron Lett. 1995, 36, 4059-4062.
  
  1. A New Synthesis of γ-Butyrolactones via Palladium(II)-Catalysed Cyclisation Of Trimethylsilylalkynes
  P. COMPAIN, J. M. VATELE and J. GORE, Synlett 1994, 943-945.